Pressure Overload Induces Early Morphological Changes in the Heart
نویسندگان
چکیده
منابع مشابه
Early activation of p160 by pressure overload in rat heart
Torsoni, Adriana S., Priscila M. Fonseca, Daniela P Crosara-Alberto, and Kleber G. Franchini. Early activation of p160ROCK by pressure overload in rat heart. Am J Physiol Cell Physiol 284: C1411–C1419, 2003. First published February 5, 2003; 10.1152/ajpcell.00098.2002.—We investigated the effects of acute pressure overload on activation of p160ROCK in rat myocardium. Constriction of transverse ...
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Our previous work on angiotensin II-mediated electrical-remodeling in canine left ventricle, in connection with a long history of other studies, suggested the hypothesis: increases in mechanical load induce autocrine secretion of angiotensin II (A2), which coherently regulates a coterie of membrane ion transporters in a manner that increases contractility. However, the relation between load and...
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Background: Esophagectomy is considered to be the main treatment for esophageal malignancies. Among the different methods, transhiatal approach can cause less damage to patients and is widely used however, manipulation of esophagus result in heart rate and blood pressure variations. The aim of this study was to investigate changes in blood pressure and heart rhythm during transhiatal esophagect...
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AIMS Development of heart failure is known to be associated with changes in energy substrate metabolism. Information on the changes in energy substrate metabolism that occur in heart failure is limited and results vary depending on the methods employed. Our aim is to characterize the changes in energy substrate metabolism associated with pressure overload and ischaemia-reperfusion (I/R) injury....
متن کاملApoptosis in pressure overload-induced heart hypertrophy in the rat.
Pressure overload induces cardiac growth in the rat, which implies the hypertrophy of cardiac muscle cells and proliferation of nonmuscle cells. The cardiac cell loss observed in parallel has generally been attributed to necrosis. Using an in situ assay, we demonstrated a phase of apoptosis or programmed cell death during the first 7 d after pressure overload with a peak at day 4 while cardiac ...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2012
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2012.06.015